Spinal muscular atrophy (SMA) is a genetically heterogeneous group of hereditary neurologic diseases and one of the types of motor neuron illness. Motor neurons are nervous cells of the spinal cord that set in motion the muscles necessary for executing motor functions of the human body.
The underlying mechanism of this disease is related to progressive degeneration of motor neurons located in anterior horns of the spinal cord, and in some cases – to motor nuclei of the brain stem. Every patient with SMA has a mutation in the survival motor neuron gene, producing a protein that is important for the normal functioning of motor neurons. Absence of this protein leads to atrophy of nervous cells, diminishing of their sizes and death resulting in muscle weakness.
Clinical symptoms of SMA are the following:
We have positive experience of treatment of acquired and genetic diseases affecting spinal motor neurons. Treatment with stem cell allows for attaining remission in 75% of cases, and for diminishing neurogenic dystrophy manifestations in SMA patients in 92% of cases.
||Rezultat tretmana fetalnim matičnim ćelijama zavisi od: težine bolesti, starosne dobi pacijenta, doslednosti i privrženosti medikaciji i režimu. Rezultati tretmana, prezentovani na ovom sajtu, su individualni za svaki klinički slučaj.|