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|1.||What stem cells are used in your clinic (adult stem cells, bone marrow stem cells, cord blood stem cells, fetal stem cells)?
We use 7–12 weeks old fetal stem cells harvested from legally aborted embryos and subjected to multiple safety testing. These cells preserve their pluripotent properties (ability to differentiate into cells of different germ layers: mesenchymal, ecto- and endodermal) and are the most effective in different diseases and conditions.
|2.||What is the advantage of fetal stem cells in comparison with other types of stem cells (adult, cord blood, animal cells)?
|3.||Are there adverse side effects related to FSC treatment?
No. Over the last 22 years no side effects associated with the FSC treatment have been observed.
|4.||How long does the treatment last?
Average duration of FSC treatment course varies from 2 to 5 days and depends on the diagnosis, history of illness, complications or concomitant diseases. In order to inform the patient about the time needed for treatment, we require providing us with basic medical data.
|5.||How is the treatment performed?
FSC treatment is administrated intravenously into the arm’s vein and/or via subcutaneous injections mainly in the frontal abdominal wall.
|6.|| How many days does the patient need to stay at the clinic after the treatment (rehabilitation period)?
There is no need to have a post-treatment rehabilitation as treatment is minimally invasive and doesn’t require any rehabilitation that is why a patient can come back to ordinary mode of life after finishing the treatment.
|7.||Is this in- or outpatient treatment?
This is outpatient treatment taking 4–5 hours a day. During the treatment, the attendant may stay in the hospital room together with the patient, especially when the patient needs assistance. Only patients in very advanced condition are left in the clinic during the treatment.
|8.||Can the treatment result in teratomas or other tumors?
No. Fetal Stem Cell treatment can not cause teratomas or any other tumors. Over the last 22 years, no post-treatment cancer cases were reported by any EmCell patient.
|9.||How soon is it possible to see the effect of treatment?
Post-transplantation effects develop in 2 stages:
Stage I (suspensional) – development of quick effects several hours after transplantation of fetal stem cells (TFSC). These effects make Syndrome of Early Post-Transplantation Improvements: improvement of general condition, less fatigue, better workability and appetite, temperature drop. This syndrome is most vividly manifested in patients with advanced diseases and severe intoxication. Syndrome of Psychofunctional Changes is also reported at this stage: decreased somatic depression, improved emotional state and cognitive processes.
Stage II (cell effects) begins 1–2 months after transplantation and is associated with cell count build-up in the diseased organ or system and subsidence of the disease symptoms: stabilization of hematopoiesis, improvement of immunity, inhibition of progression, lesser degree of dystrophy of different organs and systems including brain, liver, kidney, skin, bowel, cartilages, bones, heart, vessels etc., inhibition of inflammatory processes, increased Karnofsky’s Index, and life quality improvement. These effects are associated with cytokine cascade (formation of biologically active substances – cytokines, cytokinines) taking place for 15–40 days.
|10.|| Are there stem cells in an adult body?
Yes, in adult tissues, stem cells are present during lifetime. They restore tissues and create new specialized cells to substitute for those dead due to apoptosis (natural death of cells). For instance, stomach lining cells live only 5 days, while erythrocytes traveling in the vessels all over the body and making more than 2 000 km during lifetime live about 120 days. Epidermis has to be restored every two weeks. According to leading scientists, adult liver regenerates every 300–500 days. The above examples show how intensive body tissue regeneration processes are. As we age, stem cell count decreases, and if stem cell/bone marrow cell ratio in a newborn baby is 1/10,000, in teenagers – 1/100,000, then by the age of 50 it amount to 1/500,000, 70 – 1/1,000,000. That is why the issue of cell pool replenishment and activation of one’s own stem cells is the key one for finding solutions on how to live healthy, longer and stay young. The potential of fetal stem cell transplantation (TFSC) for treatment of presently incurable (ALS, multiple sclerosis, cancer) and genetic (Duchenne and Becker muscular dystrophy, SMA, genetic metabolic disorders) is tremendous.
|11.|| What are the differences between fetal and adult stem cells?
Adult stem cell is thought to be an undifferentiated cell, found among differentiated cells in a tissue or organ. These cells can renew itself and can differentiate to yield major specialized cell types within a tissue or organ in which these cells are placed. The primary roles of adult stem cells in an organism are to maintain and repair the tissue and organ in which they are found. Adult stem cells can be identified in many organs and tissues, including brain, bone marrow, peripheral blood, blood vessels, skeletal muscle, skin, teeth, heart, gut, liver, ovarian epithelium and testis. Typically, there is a very small number of stem cells in each tissue and organ and if these cells are removed from the body their capacity to divide becomes limited, thus it is difficult to make a generation of large quantity of stem cells. Besides, adult stem cells express histocompatibility antigens which require HLA-based donor-recipient compatibility, including individual antigens, or immunosuppression.
The fetal stem cells are the pluripotent stem cells, which are often termed ‘true’ stem cells because they have a potential to differentiate into almost any cell in the body. It means that under the right circumstances, stem cells which are isolated from fetus can produce almost all types of the cells in the body. Fetal stem cells provide a chance to obtain a renewable source of healthy cells and tissues to treat a wide range of diseases. .
|12.|| How are fetal stem cells different from cord blood cells?
1. Proliferative potential of cord blood cells is lower than that of fetal stem cells.
2. Cord blood cells are polypotent, not pluripotent.
3. Cord blood stem cells express histocompatibility antigens, therefore in order to ensure their engraftment in the recipient’s body, immunosuppression is needed.
|13.|| Are there contraindications?
The list of main contraindications is not large, but it should be carefully considered:
|14.|| Do you have a clinic and provide treatment in any other country, apart from Ukraine, for example, in Mexico, China, Thailand, etc.?
The clinic in Ukraine is the only one we have, and Kyiv is the only place where we provide our treatments.
We do have representatives in various countries listed on our homepage, but they serve as contact points and intermediaries for people looking for stem cell treatment. They also gather medical information for our potential patients.
|15.|| How is it possible to pay for the treatment?
Payment is to be made via bank transfer or against the invoice.
|16.||What is the price of the treatment?
Price of the treatment is defined by many factors such as: diagnosis, patient’s condition, number of types of cells, which are used during the treatment.