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News about stem cells
Stem cell treatment protects bone marrow from damaging chemotherapy effects in cancer patients
12 May
Stem cell therapy can protect cancer patients from damaging side-effects of chemotherapy, a new trial in the US suggests.
12 May
Stem cell therapy can protect cancer patients from damaging side-effects of chemotherapy, a new trial in the US suggests.
New Approach to Treating Muscular Dystrophy With Stem Cells
05 May
Scientists from the Lillehei Heart Institute (University of Minnesota) have developed a new efficient process of making muscle cells from human stem cells and for the first time ever effectively treated with these cells muscular dystrophy in a mice model.
05 May
Scientists from the Lillehei Heart Institute (University of Minnesota) have developed a new efficient process of making muscle cells from human stem cells and for the first time ever effectively treated with these cells muscular dystrophy in a mice model.
A New Brain Stem Cell Discovered
29 April
Adult brain contains stem cells, and Researchers at Lund University (Switzerland) found a new type of these cells.
All news
29 April
Adult brain contains stem cells, and Researchers at Lund University (Switzerland) found a new type of these cells.
Hemopoietic Cells of Human Fetal Liver in Treatment of Cytostatic Myelodepression in Patients Suffering from Solid Tumors
Snigyr Nataliya, Smikodoub Alexander
Cell Therapy Clinic of National Medical University and Embryonic Tissues Center "EmCell"
Observed were 16 patients suffering from various solid tumors and receiving radiation and/or intensive polychemotherapy. All the patients manifested cytostatic myelodepression in the form of leukocytopenia, anemia, and less frequently thrombocytopenia. To restore hemopoiesis and to form antitumoral immunity, the use was made of hemopoietic cells of human fetal liver.
Transplanted were hemopoietic cells of human fetal liver obtained from the liver of one embryo aged 6 to 12 weeks, and cryopreserved with dimethylsulfoxide. Prenatal and fetal diagnostics and tests for bacterial sterility were carried out. Such indices were determined as CPU-GM, CFU-GEMM, and CD34+. Hemopoietic cells of human fetal liver were administered intravenously, drop-by-drop.
After transplantation, syndrome of the early posttransplantation state improvement was observed in patients: weariness decreased, appetite improved, body temperature normalized.
Amounts of leukocytes and thrombocytes in peripheric blood increased on the 5th to 7th day after transplantation. Hemoglobin and erythrocytes amounts restored more slowly, after 7 to 14 days.
Transplantation of hemopoietic cells of human fetal liver allowed to carry out full-scale treatment of patients. Subsequent cytostatic therapy caused less pronounced myelodepression. Patients required hemotransfusion and taking antibiotics less than before.
Cell Therapy Clinic of National Medical University and Embryonic Tissues Center "EmCell"
Observed were 16 patients suffering from various solid tumors and receiving radiation and/or intensive polychemotherapy. All the patients manifested cytostatic myelodepression in the form of leukocytopenia, anemia, and less frequently thrombocytopenia. To restore hemopoiesis and to form antitumoral immunity, the use was made of hemopoietic cells of human fetal liver.
Transplanted were hemopoietic cells of human fetal liver obtained from the liver of one embryo aged 6 to 12 weeks, and cryopreserved with dimethylsulfoxide. Prenatal and fetal diagnostics and tests for bacterial sterility were carried out. Such indices were determined as CPU-GM, CFU-GEMM, and CD34+. Hemopoietic cells of human fetal liver were administered intravenously, drop-by-drop.
After transplantation, syndrome of the early posttransplantation state improvement was observed in patients: weariness decreased, appetite improved, body temperature normalized.
Amounts of leukocytes and thrombocytes in peripheric blood increased on the 5th to 7th day after transplantation. Hemoglobin and erythrocytes amounts restored more slowly, after 7 to 14 days.
Transplantation of hemopoietic cells of human fetal liver allowed to carry out full-scale treatment of patients. Subsequent cytostatic therapy caused less pronounced myelodepression. Patients required hemotransfusion and taking antibiotics less than before.