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News and articles on cancer

Stem cells Producing Cancer-Killing Toxins May Treat Brain Tumors 05 November 2014

The scientists from Harvard Stem Cell Institute and Massachusetts General Hospital have found a way to get stem cells that produce tumor-killing toxins.

Stem cell technology key to tumour killers 12 August 2013

Stem cell technology can be used to mass-produce cancer-killing immune cells designed to target different kinds of tumours, scientists have shown.

The research opens up the prospect of immunotherapy treatments helping many more cancer patients in the future.

In theory cancer can be tackled by elements of the body's own immune defences, especially white blood cells called T-cells.

Stem cell treatment protects bone marrow from damaging chemotherapy effects in cancer patients 12 May 2012

Stem cell therapy can protect cancer patients from damaging side-effects of chemotherapy, a new trial in the US suggests.

Arsenic Spurs Tumor Growth, Making Stem Cells Cancerous 08 April 2012

National Institutes of Health (NIH) researchers have found how inorganic arsenic can make stem cells cancerous and spur tumor growth.

All news

Cancer

Indications for transplantation of fetal stem cells in case of cancer

In case of malignancies, we are using patented methods of treatment with stem cells. These methods have proved their efficacy, have been approved by the Ministry of Health on April 20, 1999 and have been recommended for use in clinical practice. Transplantation of fetal stem cells is possible at all stages of oncological diseases:

  • At the initial stage of treatment, if surgery (tumour removal) cannot be started due to such complications as anemia, weakness, wasting, thrombocytopenia, depression, etc., transplantation of fetal stem cells prior to the tumour removal operation provides for the best preparation of the patient to surgery and best tolerability of the latter; it also accelerates the postoperative wound healing process, minimizes consequences and complications of anaesthesia, and reduces the duration of the post-surgery rehabilitation period that allows for more rapid continuation of comprehensive treatment. In patients treated with the method of fetal stem cell transplantation prior to the operation, best tolerability of chemotherapy courses had been observed. Probability of metastatic process development diminishes as a result of increased anti-tumour immunity.
  • During the course of chemotherapy and radiotherapy (irradiation), in case of such complications as leukopenia, agranulocytosis, thrombocytopenia, anemia, hepatitis, enteropathy, wasting, depression, alopecia, etc., transplantation of fetal stem cells promotes rapid (5 to 7 days) restoration of peripheral blood parameters after chemotherapy, improvement of the overall condition, and helps prevent complications. Transplantation of fetal stem cells provides an opportunity for carrying out more large-scale and intensive chemotherapy with a minimum risk without violating its timeframe.
  • After chemotherapy and radiotherapy (irradiation), transplantation of fetal stem cells is instrumental in restoring anti-tumour immunity (including NK cells) and haemopoesis; it contributes to improvement of patient’s overall condition, decrease in weakness, as well as to improvement of their psycho-emotional status and quality of life.

Post-transplantation effects

Solid experience in cancer treatment allowed us to distinguish two stages in post-transplantation period that are different in time of development and clinical manifestations.

The first stage lasts for about one month and is characterized by emergence of early clinical symptoms that develop within a few hours after transplantation of fetal stem cells. We have described the early post-transplantation improvement syndrome: improvement in overall condition and appetite, decline in body temperature, diminishing weakness and sweating, restoration of self-care ability and increase in performance. This syndrome mostly occurs in patients with symptoms of severe intoxication and is often observed in patients with severe clinical course of the disease.

Also, a syndrome of psycho-functional changes is observed: reduction of somatic depression, improvement of emotional status, cognitive abilities, memory, and conative component.

The second stage of cell effect begins within one to two months after transplantation. It is related to reduced clinical manifestations of the disease and is characterized by stabilisation of haemopoesis, improvement of the immunological profile, reduction of inflammatory effects, elevation of Karnovsky index, and improved quality of life.

Stem cell therapy contributes to formation of anti-tumour immunity; that can be used for preventing oncological diseases, as well as with the purpose of avoiding relapse and metastatic process.

Duration of cancer treatment course at Cell Therapy Center EmCell, as a rule, totals 2 days.
 
Application of Fetal Stem Cell Suspensions in Complex Treatment of Cancer Patients (poster presentation).
Ukrainian, jpg, 2.6 Mb
 

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