Main Effects and Specific Features of Embryonic Stem Cell Transplantation

Manifestations of the main effects are characterized by specific features.

1. Shortly after transplantation, there develop positive changes in emotional and volitional aspects of psychological sphere: increased vigor, improved feeling of inner strength, belief in favorable result of treatment, absence of depression, improvement of mood and mental creativity, diminished and with time, disappearing neurotic manifestations. The most important part of all these changes is marked enhancement of the will component and raise of the patient’s spirit. In some diseases, these changes are rather considerable, obvious and very important, grim psychological background associated with severe diseases taken into consideration.

2. Noted is quick and significant increase of mental capacity: concentration and ability to maintain attention, clarity of sensation, thinking, speech and memory. Stabilization of vigilance and emotional condition is also reported. Neurotic manifestations, irritability, petulance, quick and chronic fatigue, somnolence, apathy - disappear.

   Improvement of sleeping pattern: insomnia disappears, sleep becomes refreshing and recuperative, observed is notable improvement of night res.

   Duration of efficient mental work is prolonged.

   The most marked changes are observed in patients with brain disorders, degenerative processes of brain tissues, senility symptoms, or impaired or weakened brain activity.

3. Increase of activity, persistency, and desire for movement. Active physical load during this period quickly restores good physical shape. Weight is normalized: overweight people loose weight, underweight people gain weight. Appearance gains freshness; improved are walking, attitude, body vigor. Family and friends notice general rejuvenation of the patients. Range of motions increases: in some cases, movements, that were impossible or considered to be lost, reappear shortly after ES transplantation. Coordination of movements is also improved. Noted is also termination of deterioration of nervous system, which is proved by decreased manifestations.

4. Restored functional activity of impaired and damaged internal organs and tissues leads to steady recovery. Observed is active and quick restoration of suppressed hematopoiesis, e.g. normalization of quantitative parameters of peripheral blood (hemoglobin, erythrocytes, leukocytes, lymphocytes, platelets), as well as bone marrow count, provided it is impaired. Markedly quick restoration is observed after chemo- or radiotherapy in cancer patients with advanced agranulocytosis.

Stimulation, correction and restoration of immune status is also observed in chronic inflammatory processes in the form of disappearance of many viral, mycoplastic, and fungal lesions. Autoimmune processes are either terminated or interrupted. Frequency of acute respiratory diseases decreases, and risk of their transition into chronic forms reduces. ESCT is very good prophylactic means for cancerous diseases developing when immune control over malignant cells is weakened.

Trophic functions are substantially activated by means of many mechanisms. Restored or improved blood circulation normalizes nutrition and functioning of organs, tissues, skin, etc. Kidney and liver functions improve significantly. Observed is marked increase of both libido and potency.

Recovery patterns and its progress vary in accordance with the patient’s state of health. Improvement and normalization are extended to the whole physiological supply and support of the body, including nervous, muscle, immune, transport, sexual, digestive, and excretory systems, hematopoiesis, blood circulation, etc.