De En Es It
16 YEARS OF INTERNATIONAL CLINICAL EXPERIENCE IN TRANSPLANTATION OF HUMAN EMBRYONIC/FETAL STEM CELLS. REVIEW
THE WORLDS LARGEST CLINICAL EXPERIENCE IN EMBRYONIC STEM CELL TRANSPLANTATION FOR VARIOUS DISEASES AND CONDITIONS

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Case Report

HIV infection in patient G. was diagnosed in 1990 during regular examination. For a long period, the condition was stable and good. In May, 1993, CD4+ index was noted to decrease down to 300/mm3, due to which fact on June 4, 1993 first transplantation of hematopoietic human embryonic liver cells was carried out, and on August 18, 1993, the second transplantation. Within 2 weeks CD4+ count increased up to 1200/mm3 and, in spite of some periodic fluctuations, this parameter remains high up to now (900/mm3) (Table).

General condition of the patient is good; he maintains physical ability to work although had to change his job (sea navigator) because of disclosure of his diagnosis.

Within the last three years, he suffered from several catarrhal diseases, though without significant deterioration of general condition. When he was sick, he received regular preparations (biseptol for bronchitis, multivitamins for acute respiratory infections), and did not take azidothymidin.

Head of the Cell Therapy Clinic
of National Medical University and Center "EmCell"
professor Alexander Smikodoub.


Immunology of HIV-infected patient G., male

Date CD3+ CD4+ CD8+
01.06.93 627 280 209
04.06 1 Cell Transplantation
08.06.93 670 448 238
10.06.93 651 485 256
17.06.93 543 456 238
08.07.93 868 348 319
27.07.93 634 797 838
05.08.93 585 420 155
18.08 2 Cell Transplantation
02.09.93 1870 1227 1110
14.09.93 972 789 597
16.09.93 976 623 690
30.09.93 523 275 599
16.11.93 927 690 1028
28.12.93 460 380 445
8.02.94 1188 146 1150
21.04.94 1643 455 1335
24.05.94 1973 490 1378
21.06.95 930 700 950
4.12.95 1020 900 1100

News
2008-09-25
Prof. Alexander I. Smikodub attended European Congress on Anti-Aging and

Prof. Alexander I. Smikodub attended European Congress on Anti-Aging and Aesthetic Medicine held in Dusseldorf, Germany on September 11-14, 2008 as ...
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Publications

25. Summary 2007

Participation in National and International Congresses, Conferences and Meetings III National Congress on Bioethics. Kyiv, Ukraine, October 8 – 11, 2007. IV Meeting of Transplantologists of Ukraine. ...
  Publications in English (1996-2003)
 
Patents

Medicinal preparation based on fetal cell suspension having immune substituting effect for patients with acquired immune ...
 
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