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Stem cell news Stem cells turned into different parts of the body in the lab 13 April 2014

Scientists from North London hospital grow ears, noses, and blood vessels in the laboratory from stem cells.

Moderate exercise results in stem cell activation and muscle regeneration 06 April 2014

The scientists have proved once more the positive impact of exercises on the body. In addition to its effects on heart, weight, and overall health, moderate exercising helps to restore muscle mass which usually diminishes as we age.

Stem cells from baby teeth and autism treatment 30 March 2014

Dr. Alysson Muotri, the reseacher of UCSD, is devoted to finding cures from autism spectrum disorders. For that purpose, he organized collection of stem cells from milk teeth from both autistic and non-affected kids.

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About EmCell

Cell Therapy Center EmСell: Past and Present

Following successful animal trials started in the 1970’s by a group of young scientists at the National Medical University, in 1985, EmCell founders started working with fetal stem cells and later applying them in clinical practice. They were prompted by the experimental work with animals that had proved positive impact of stem cells harvested from animal fetuses on neurodystrophy in denervated organs and tissues.  In 1987, stem cells were applied by EmCell founders, for the first time, for treatment of cytostatic myelodepression and aplastic anemia in the National Medical University of Ukraine.

In 1991, after obtaining the permission of the Ukrainian Health Ministry, fetal stem cells started to be widely used for different diseases and conditions such as dystrophy, diseases causing cell deficit, sclerosis and malignant processes. A group of doctors developed and introduced a reliable and safe method of fetal stem cell treatment that proved effective for certain diseases and conditions and showed good results in different patients. At the same time, no side effects or complications were reported, which allowed for extension of the range of diseases in which stem cell therapy could be applied.

We were the first in the world to develop our own stem cell treatment protocols for such diseases as multiple sclerosis, diabetes, and autism.

In 1994, our extensive clinical experience led to the launching of the world’s first specialized cell therapy center, EmCell, that used fetal stem cells for therapeutic purposes, in Kyiv, Ukraine.

Over the years, we have performed more than 8,000 fetal stem cell transplantations to patients from 92 countries around the world. Our treatment has helped to save and prolong patients’ lives, restore their tissue and organ functions, and achieve positive results in treating diseases in which routine methods have proved ineffective.

All fetal stem cell treatment methods used at EmCell are patent-protected in different countries. EmCell currently holds 19 patents in the US, the Netherlands, Greece, Russia, and Ukraine. EmCell was the first in the world to obtain patents for clinical application of fetal stem cell suspensions: our first patent application dates back to October 18, 1993.  Our patents cover methods of hematopoietic stem cell harvesting, creation of cell suspensions, treatment of autism, multiple sclerosis, diabetes mellitus, aplastic anemia, psoriasis, cancer etc.

Since 1991, 7 MMS theses were written on application of fetal stem cells in different diseases and conditions including diabetes, intestinal diseases, cancer, rheumatoid arthritis etc.

Starting from 1994, we operated under a general license for medical practice. In 2011, a new regulation required all clinics working with stem cells to apply for a special license, the only one allowing legal manipulations with stem cells. EmCell was also the first in Ukraine to receive the state license for fetal cell bank operation.

BBC documentary called EmCell the "Last Hope Clinic" because we treated and followed-up the most complicated clinical cases from all over the world.
During the years of intensive work, EmCell team won international acclaim in the field of research and clinical application of fetal stem cells. EmCell professionals authored more than 300 scientific works published in the national as well as international magazines and congress proceedings.

Today, EmCell consists of a Clinical Department and a laboratory complex operating in its own 1,200 sq m renovated building with 8 VIP rooms offering patients comfort and hospitality.

The Clinical Department employs highly qualified, experienced doctors with different specializations who also hold scientific degrees and have numerous patents to their names. Our professional team of nurses and assistants completes our clinical department staff.

The Clinical Department offers both diagnostic (ultrasound, ECG, EchoCG, Doppler, spirography etc.) and consultative services.

The Laboratory Complex consists of five EmCell lab units functioning as a single department:

  • Clinical-Diagnostic Laboratory is a place where lab tests for diagnostic and follow-up purposes are performed and, if necessary, where the treatment regimen is adjusted (сomplete blood count, blood chemistry, cytology etc.).
  • Biotechnology Laboratory is a place where fetal stem cell suspensions are produced in accordance with original technology developed by our specialists.

Biotechnological stages of work with fetal cell suspensions include:

  1. Timely, safe, and ethically approved collection of high quality fetal material in gynecological departments.
  2. Preparation of fetal cell suspensions and putting them into sterile containers.
  3. Safety and viability testing of fetal cell suspensions.
  4. Programmed cryopreservation of cell transplants.
  5. Safety and viability testing of defrosted fetal cell suspensions before their use.
  6. Long-term storage of fetal cell suspensions in cryobanks.

Creation of cell suspensions and their transplantation at the same facility is a perfect combination as it guarantees the high quality of the cell transplants and allows achieving the best effects.

  • R&D Department is a place where our specialists continually work on the advancement and improvement of fetal stem cell suspension quality.  Now, our specialists work on specification of each fetal cell suspension by applying flow cytometry and culturing in semi-liquid agar media (modified Pike and Robinson’s method).  This will enable us to characterize differential activity and proliferative potential of the cells we use in the clinic and predict positive outcome of the treatment with more precision.
  • PCR Laboratory is a place where precise, high-quality regular and express tests take place for both clinical and biotechnological purposes. To ensure safety, our fetal stem cell suspension are real-time PCR tested for multiple viruses and bacteria including HIV-1/2, HCV, HBV, CMV, YSV-1/2, Treponema pallidum, Chlamidium trachomatis, Mycoplasma genitalis, Ureaplasma Urealyticum and Parvum etc.
  • The Cryobank is a place where more than 10,000 individual samples of fetal stem cell suspensions, the core of our treatment, are safely stored in a modern cryostorage facility. We use a unique method of programmed freezing allowing for preserving high quality of fetal stem cell suspensions.

We care about our patients and our reputation worldwide.  We keep up to date with modern technology and innovations and advance our methods of work in order to ensure the highest quality and safety standards of the cells.  Our specialists in all fields continuously work on the advancement of stem cell suspension preparation and proper application technologies, they prepare new patents and write experience-based articles on different aspects of stem cell application, learn and introduce new methods and approaches.  All of this is for the patient’s benefit.   The best award for EmCell is successful treatment and improvements in our patients, their words of gratitude and smiles on their faces.